Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffuse loss of sensitivity in early glaucoma.

D B Henson1, P H Artes, B C Chauhan

  • 1Department of Ophthalmology, University of Manchester, United Kingdom. david.henson@man.ac.uk

Investigative Ophthalmology & Visual Science
|December 10, 1999
PubMed
Summary

Early glaucoma often causes diffuse visual field loss, affecting even the most sensitive areas. This suggests that localized vision loss in glaucoma is uncommon and not due to pupil size or media opacity.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ISCEV and IPS guideline for the full-field stimulus test (FST).

Documenta ophthalmologica. Advances in ophthalmology·2024
Same author

Assessing retinal ganglion cell damage.

Eye (London, England)·2017
Same author

Rates of glaucomatous visual field change after trabeculectomy.

The British journal of ophthalmology·2016
Same author

New superior-inferior visual field asymmetry indices for detecting POAG and their agreement with the glaucoma hemifield test.

Eye (London, England)·2015
Same author

Rates of retinal nerve fibre layer thickness change in glaucoma patients and control subjects.

Eye (London, England)·2012
Same author

Individualised patient care as an adjunct to standard care for promoting adherence to ocular hypotensive therapy: an exploratory randomised controlled trial.

Eye (London, England)·2011

Area of Science:

  • Ophthalmology
  • Optometry
  • Visual Neuroscience

Background:

  • Glaucoma is a leading cause of irreversible blindness.
  • Early detection of glaucoma is crucial for preserving vision.
  • Understanding the pattern of visual field loss in early glaucoma is essential for timely intervention.

Purpose of the Study:

  • To determine if early primary open-angle glaucoma (POAG) is associated with diffuse loss of visual sensitivity.
  • To investigate whether the most sensitive visual field locations are affected in early glaucoma.

Main Methods:

  • Compared differential light sensitivities of the 10 most sensitive locations in the central 24 degrees using Humphrey Field Analyzer program 30-2.
  • Studied 38 pairs of age-matched subjects: one with early POAG, one with normal eyes.
  • Included subjects with prior perimetry experience, clear media, and good visual acuity.

Main Results:

  • Subjects with early POAG showed significantly lower sensitivity in the 10 most sensitive locations compared to normal subjects (median difference 1.0-2.0 dB).
  • In 60% of pairs, the seventh most sensitive location was at least 2 dB lower in eyes with POAG.
  • These differences were not attributable to variations in pupil size or media opacity.

Conclusions:

  • Early glaucomatous visual field loss commonly includes a diffuse component affecting even the most sensitive areas.
  • Purely localized visual field loss may be rare in the early stages of glaucoma.
  • Findings highlight the importance of considering diffuse sensitivity loss in diagnosing and managing early glaucoma.

Related Experiment Videos