Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyperthyroidism and concurrent thyroid cancer.

R Vaiana1, C Cappelli, P Perini

  • 1Second Division of General Surgery, Spedali Civili, Brescia, Italy.

Tumori
|December 10, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Case Report: Patient-specific 3D-printed preoperative simulation for tailored resection and reconstruction in complex vertebral tumors: a case of giant recurrent chondrosarcoma at the cervicothoracic junction.

Frontiers in surgery·2026
Same author

Standardizing the lateral fluid percussion model of trauma in marmosets (Callithrix jacchus): regional vulnerability and inflammatory response.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2026
Same author

Isolated oculomotor dysfunction with downbeat nystagmus as a rare presentation of anti-GAD autoimmunity.

Journal of neuroimmunology·2026
Same author

ANTIEPILEPTIC DRUGS AND BONE HEALTH: A COMPREHENSIVE REVIEW AND META-ANALYSIS.

Acta endocrinologica (Bucharest, Romania : 2005)·2025
Same author

Development of an ion exchange process for ammonium removal and recovery from municipal wastewater using a metakaolin K-based geopolymer.

Chemosphere·2024
Same author

Determinants of late recovery following elective colorectal surgery.

Techniques in coloproctology·2024
Same journal

End-of-life decisions and opinions: Results of E.L.D.Y.-CA.RE study carried out at Veneto Institute of Oncology, Italy.

Tumori·2026
Same journal

Quality indicators in identification and care of patients with genetic predisposition to cancer: An AIFET proposal.

Tumori·2026
Same journal

Driver vs. passenger: Primary resistance to larotrectinib in synovial sarcoma harboring concurrent SS18 rearrangement and PDE3A-NTRK2 fusion.

Tumori·2026
Same journal

Beyond the calendar: A narrative review on chronobiological drivers of prognosis in resectable NSCLC.

Tumori·2026
Same journal

Challenging the cornerstone: Toward risk-adapted follow-up in early breast cancer.

Tumori·2026
Same journal

Assessing in house comprehensive genomic profiling by liquid biopsy for NSCLC patients.

Tumori·2026
See all related articles

Thyroid cancer frequently coexists with hyperthyroidism in endemic goiter regions, affecting nearly 5% of patients. This highlights the need for systematic evaluation to rule out malignancy in hyperthyroid individuals.

Area of Science:

  • Endocrinology
  • Oncology
  • Thyroidology

Background:

  • Endemic goiter areas present unique challenges in thyroid disease management.
  • Hyperthyroidism is a common endocrine disorder with various underlying causes.

Purpose of the Study:

  • To determine the incidence of thyroid malignancy in patients with hyperthyroidism in endemic goiter regions.
  • To review existing literature on the co-occurrence of hyperthyroidism and thyroid cancer.

Main Methods:

  • Retrospective analysis of 1853 hyperthyroid patients from January 1984 to June 1998.
  • Surgical intervention in 512 patients diagnosed with Graves' disease, multinodular toxic goiter (MTG), or uninodular toxic goiter (UTG).

Main Results:

Related Experiment Videos

  • Thyroid malignancy was detected in 4.7% of hyperthyroid patients (24 individuals).
  • Cancer frequencies varied by hyperthyroid type: Graves' disease (6.4%), MTG (3.9%), and UTG (4.4%).
  • Malignancy was more prevalent in females across all hyperthyroid subgroups.

    • Conclusions:

    • The study confirms a significant association between hyperthyroidism and thyroid cancer, potentially underestimated in endemic areas.
    • A systematic approach is crucial for evaluating hyperthyroid patients to exclude underlying neoplastic degeneration.
    • Findings underscore the importance of considering malignancy in the differential diagnosis of hyperthyroidism.