Gamma probe localization of cranial bone lesions
Related Experiment Video
Updated: Oct 18, 2026
State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
G D Albert1, J C Alex, D N Krag
1Department of Surgery, University of Vermont School of Medicine, Burlington, USA.
Purpose:
Staging of cancer is essential to formulate appropriate treatment plans and to help predict prognosis. A solitary region of increased radionuclide uptake ("hot spot") on a bone scan may represent a metastasis or a masquerading lesion. Biopsy may be required to determine its histologic nature, but localization of the site may be difficult because bone scans provide poor spatial resolution.
Methods:
In two patients with breast carcinoma, radioactive technetium was administered intravenously and a gamma probe was used preoperatively and intraoperatively to identify the site of cranial bone involvement.
Results:
The lesions were resected; one was a benign fibro-osseous lesion and one was a metastatic breast adenocarcinoma.
Conclusions:
A gamma probe may be helpful in localizing the site of radioactive uptake identified by bone scan.
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