Related Experiment Video
Updated: Oct 18, 2026

High-throughput Detection Method for Influenza Virus
Published on: February 4, 2012
Identification of a bovine coronavirus packaging signal
1Division of Molecular Virology, Baylor College of Medicine, Houston, Texas 77030, USA.
Abstract:
A region of the bovine coronavirus (BCV) genome that functions as a packaging signal has been cloned. The 291-nucleotide clone shares 72% homology with the region of mouse hepatitis coronavirus (MHV) gene 1b that contains the packaging signal. RNA transcripts were packaged into both BCV and MHV virions when the cloned region was appended to a noncoronavirus RNA. This is the first identification of a BCV packaging signal. The data demonstrate that the BCV genome contains a sequence that is conserved at both the sequence and functional levels, thus broadening our insight into coronavirus packaging.
Related Concept Videos
Bacterial Signaling
DNA Packaging

