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Complications in skull base surgery for malignancy.

P J Donald1

  • 1Department of Otolaryngology-Head and Neck Surgery and the Center for Skull Base Surgery, University of California, Davis, Sacramento, USA.

The Laryngoscope
|December 11, 1999
PubMed
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Skull base surgery for cancer has a 50.5% complication rate, with cerebrospinal fluid leaks and wound breakdown being most common. Prevention and management strategies are crucial for improving outcomes in these complex procedures.

Area of Science:

  • Neurosurgery
  • Surgical Oncology

Background:

  • Skull base surgery is complex, often involving malignancy that has spread intracranially.
  • Understanding complication rates is vital for patient care and surgical planning.

Purpose of the Study:

  • To review skull base surgeries for malignancy.
  • To determine the complication rate.
  • To outline prevention and management strategies.

Main Methods:

  • Retrospective review of 107 intracranial/extracranial operations.
  • Analysis of 98 patients undergoing skull base surgery for cancer at UC Davis Medical Center.
  • Data collection on operation type, cause of death, and complications.

Main Results:

Related Experiment Videos

  • A 50.5% complication rate was observed.
  • Most common surgical complications included cerebrospinal fluid leak (11.2%) and wound breakdown (15%).
  • Most common medical complications were pneumonia (6.5%) and cardiac disturbance (4.7%).

    • Conclusions:

    • Skull base surgery for intracranial spread of head and neck cancer has a perioperative death rate under 4%.
    • Major complications occurred at an acceptable rate.
    • Previous surgery was associated with a significant increase in complications.