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Updated: Jul 23, 2026

Collecting Sleep, Circadian, Fatigue, and Performance Data in Complex Operational Environments
Published on: August 8, 2019
A multinational study of the relationships between nighttime urinary melatonin production, age, gender, body size,
L Wetterberg1, T Bratlid, L von Knorring
1Psychiatric Research Center University of Tromsø, PFFT at Asgård Hospital, N-9291 Tromsø, Norway.
Abstract:
Overnight urines were collected each month for 12-16 months from 321 normal subjects at 19 medical centers in 14 countries distributed on 5 continents at latitudes from 31 01 South to 77 00 North. Mean melatonin concentration was found to negatively correlate with age, weight, and height. When the sexes were considered separately melatonin only correlated with age for female and with age and weight for males. A weak correlation with latitude, but not longitude, was also found.
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