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The EMBL nucleotide sequence database.

W Baker1, A van den Broek, E Camon

  • 1EMBL Outstation-The European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

Nucleic Acids Research
|December 11, 1999
PubMed
Summary
This summary is machine-generated.

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The European Molecular Biology Laboratory (EMBL) Nucleotide Sequence Database offers free access to updated molecular data through international collaboration. It provides network services and tools for sequence similarity searching, aiding researchers in bioinformatics.

Area of Science:

  • Bioinformatics
  • Molecular Biology Databases
  • Genomic Data Management

Background:

  • The European Molecular Biology Laboratory (EMBL) Nucleotide Sequence Database is a key resource for molecular biology.
  • It is maintained collaboratively by the European Bioinformatics Institute (EBI), DNA Data Bank of Japan (DDBJ), and GenBank (USA).

Purpose of the Study:

  • To describe the EMBL Nucleotide Sequence Database, its collaborative maintenance, data submission methods, and accessibility.
  • To highlight the network services and tools available for accessing and analyzing sequence data.

Main Methods:

  • Data is exchanged daily among collaborating databases (EMBL, DDBJ, GenBank).
  • Individual authors and genome projects contribute data via WEBIN or automatic procedures.
  • Database releases are published quarterly.

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  • Network services and EBI's Sequence Retrieval System (SRS) provide access and integration of molecular databases.

    • Main Results:

    • Free access to up-to-date nucleotide sequence data is available via Internet and WWW interfaces.
    • The SRS integrates multiple specialized databases, including nucleotide and protein sequences.
    • Tools like BLITZ, FASTA, and BLAST are available for sequence similarity searching against the EMBL database and SWISS-PROT.

    Conclusions:

    • The EMBL Nucleotide Sequence Database, through international collaboration and advanced network services, provides a vital, accessible resource for molecular biology research.
    • It facilitates efficient data sharing and analysis for the scientific community.