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The European small subunit ribosomal RNA database
Y Van de Peer1, P De Rijk, J Wuyts
1Departement Biochemie, Universiteit Antwerpen (UIA), Universiteitsplein 1, B-2610 Antwerpen, Belgium.
Nucleic Acids Research
|December 11, 1999
Summary
The European Small Subunit Ribosomal RNA database offers comprehensive data on rRNA structures and related information. It provides easy online access to sequences for research and analysis.
Area of Science:
- Molecular Biology
- Bioinformatics
- Genomics
Background:
- Ribosomal RNA (rRNA) is crucial for protein synthesis and cellular function.
- Comprehensive databases are essential for studying rRNA structure and evolution.
- Existing rRNA databases may lack specific details or accessibility.
Purpose of the Study:
- To establish a centralized, curated European database for Small Subunit (SSU) Ribosomal RNA.
- To compile primary and secondary structure information for complete or near-complete SSU rRNAs.
- To integrate associated data like literature references and taxonomic information.
Main Methods:
- Curating and collecting SSU rRNA sequence data from various sources.
- Ensuring data quality for primary and secondary rRNA structures.
- Developing a World Wide Web interface for database access and retrieval.
Main Results:
- A comprehensive collection of SSU rRNA sequences with structural information.
- Inclusion of literature references and taxonomic data for each sequence.
- An accessible online platform for querying and retrieving data.
Conclusions:
- The European SSU rRNA database serves as a valuable resource for molecular biology and bioinformatics research.
- Facilitates the study of rRNA structure, function, and evolution.
- Enhances accessibility to critical genetic information for the scientific community.