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Infant immunization coverage in Italy: estimates by simultaneous EPI cluster surveys of regions. ICONA Study Group
S Salmaso1, M C Rota, M L Ciofi Degli Atti
1Infectious Disease Unit, Istituto Superiore di Sanità (ISS), Rome, Italy.
Insights
Italian children aged 12-24 months show high mandatory vaccine coverage (over 94%) but suboptimal rates for optional vaccines like measles and Hib. Pertussis vaccine coverage significantly improved.
Area of Science:
- Pediatric infectious diseases
- Public health surveillance
- Vaccinology
Background:
- Assessing childhood immunization coverage is crucial for disease prevention.
- Understanding regional disparities in vaccine uptake is essential for public health planning.
- The ICONA Study aimed to evaluate vaccination status in Italian children.
Purpose of the Study:
- To estimate mandatory and optional immunization coverage in Italian children aged 12-24 months.
- To identify regional variations in vaccine uptake.
- To determine reasons for vaccine refusal or delay.
Main Methods:
- A cross-sectional survey conducted in 19 Italian regions in 1998.
- Utilized the Expanded Programme of Immunization (EPI) cluster sampling technique.
- Included interviews with parents of 4310 children born in 1996.
Main Results:
- Overall mandatory vaccine coverage (oral poliovirus, diphtheria-tetanus, hepatitis B) exceeded 94%.
- Only 79% received vaccines within the first year of life.
- Pertussis coverage rose to 88%, measles coverage was 56%, and Hib coverage was 20%.
Conclusions:
- Mandatory immunizations in Italy are largely satisfactory.
- Significant improvement in pertussis coverage is noted, likely due to acellular vaccines.
- Enhanced education for parents and physicians is needed to boost optional vaccination rates.
Abstract:
In 1998, a series of regional cluster surveys (the ICONA Study) was conducted simultaneously in 19 out of the 20 regions in Italy to estimate the mandatory immunization coverage of children aged 12-24 months with oral poliovirus (OPV), diphtheria-tetanus (DT) and viral hepatitis B (HBV) vaccines, as well as optional immunization coverage with pertussis, measles and Haemophilus influenzae b (Hib) vaccines. The study children were born in 1996 and selected from birth registries using the Expanded Programme of Immunization (EPI) cluster sampling technique. Interviews with parents were conducted to determine each child's immunization status and the reasons for any missed or delayed vaccinations. The study population comprised 4310 children aged 12-24 months. Coverage for both mandatory and optional vaccinations differed by region. The overall coverage for mandatory vaccines (OPV, DT and HBV) exceeded 94%, but only 79% had been vaccinated in accord with the recommended schedule (i.e. during the first year of life). Immunization coverage for pertussis increased from 40% (1993 survey) to 88%, but measles coverage (56%) remained inadequate for controlling the disease; Hib coverage was 20%. These results confirm that in Italy the coverage of only mandatory immunizations is satisfactory. Pertussis immunization coverage has improved dramatically since the introduction of acellular vaccines. A greater effort to educate parents and physicians is still needed to improve the coverage of optional vaccinations in all regions.
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