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Related Experiment Videos

Blastocyst transfer and monozygotic twinning.

B Peramo1, E Ricciarelli, J M Cuadros-Fernández

  • 1Clínica de Reproducción Asistida FIV-Madrid and Instituto de Bioquímica, CSIC, Madrid, Spain.

Fertility and Sterility
|December 11, 1999
PubMed
Summary

Monozygotic twinning may increase after in vitro fertilization (IVF) with blastocyst transfer. Patients should be informed about potential obstetric complications associated with these multiple gestations.

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Area of Science:

  • Reproductive Endocrinology
  • Clinical Embryology
  • Maternal-Fetal Medicine

Background:

  • Assisted reproductive technologies (ART) aim to improve pregnancy outcomes.
  • Blastocyst transfer is a common practice in in vitro fertilization (IVF).
  • The incidence of multiple gestations is a known concern in ART.

Observation:

  • Two cases of monozygotic twinning were observed following IVF with blastocyst transfer.
  • One twin pregnancy experienced fetus-to-fetus transfusion syndrome, leading to preterm delivery via cesarean section.
  • The second twin pregnancy resulted in a normal term delivery via vaginal birth.

Findings:

  • Monozygotic multiple gestations appear to be a potential outcome of IVF utilizing blastocyst transfer.
  • The occurrence of complications such as twin-to-twin transfusion syndrome is possible in these pregnancies.

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  • Pregnancy outcomes can vary significantly, ranging from complicated to normal deliveries.

    • Implications:

    • Clinicians should consider the increased risk of monozygotic twinning with IVF blastocyst transfers.
    • Informed consent discussions must include the potential for multiple gestations and associated obstetric risks.
    • Further research may be warranted to elucidate the mechanisms and precise incidence of monozygotic twinning post-blastocyst transfer.