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Related Experiment Videos

Lung biopsy: is it necessary?

R T Temes1, N E Joste, C R Qualls

  • 1University of New Mexico Health Sciences Center, Department of Surgery, Albuquerque, NM 87131, USA. Ttemes@salud.unm.edu

The Journal of Thoracic and Cardiovascular Surgery
|December 14, 1999
PubMed
Summary
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Elective and urgent lung biopsies in immunocompetent patients offer acceptable mortality and yield significant therapeutic changes. Emergency lung biopsies carry high mortality and limited therapeutic benefit, advising against their use in stable patients.

Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Critical Care Medicine

Background:

  • Lung biopsy is a critical diagnostic tool but carries significant mortality risks.
  • Assessing the risk-benefit ratio of lung biopsy is essential, particularly in immunocompetent patients.

Purpose of the Study:

  • To evaluate the outcomes of diagnostic lung biopsies in immunocompetent patients.
  • To determine if the benefits of lung biopsy justify its continued use.

Main Methods:

  • Retrospective review of diagnostic lung biopsies performed at three university-affiliated hospitals.
  • Data collected from July 1992 to December 1998, encompassing 75 patients.

Main Results:

  • Elective (0% mortality) and urgent (18% mortality) lung biopsies showed acceptable operative mortality.

Related Experiment Videos

  • Significant therapeutic changes occurred in 60% of elective and 94% of urgent procedures.
  • Emergency lung biopsies had a 54% mortality rate and rarely led to changes beyond immunosuppression.

    • Conclusions:

    • Elective and urgent lung biopsies are appropriate for immunocompetent patients due to acceptable mortality and therapeutic benefits.
    • Emergency lung biopsies should be avoided in stable patients; empirical immunosuppression is recommended if condition deteriorates.