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Related Experiment Videos

Morphological pattern and frequency of thyroid tumors.

S H Shah1, S Muzaffar, I N Soomro

  • 1Department of Pathology, Aga Khan University Hospital, Karachi.

JPMA. the Journal of the Pakistan Medical Association
|December 22, 1999
PubMed
Summary
This summary is machine-generated.

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Thyroid cancer is more common in females. Papillary carcinoma is the most frequent histological type, particularly in women and those in their third to fifth decades of life.

Area of Science:

  • Oncology
  • Pathology
  • Endocrinology

Background:

  • Thyroid cancer represents a significant global health concern.
  • Understanding the epidemiological characteristics and histological subtypes is crucial for effective management.

Purpose of the Study:

  • To determine the frequency of thyroid cancer.
  • To analyze the prevalence of different histological types of thyroid tumors.
  • To investigate the relationship between tumor types, age, and sex.

Main Methods:

  • Retrospective analysis of consecutive malignant thyroid tumor cases diagnosed between 1995-1997.
  • Histopathological evaluation using H&E stained sections from paraffin-embedded tissues.
  • Special stains and immunohistochemistry were employed as needed.

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Main Results:

  • Thyroid cancer accounted for 1.2% of all malignant tumors (103 out of 8541).
  • Thyroid tumors were more prevalent in females (female to male ratio of 2.6:1).
  • Papillary carcinoma was the predominant histological type (69%), followed by follicular (11.6%) and medullary (9.7%) carcinomas.

Conclusions:

  • Thyroid cancer exhibits a higher incidence in females.
  • Papillary carcinoma is the most common histological subtype in both sexes.
  • Peak incidence for papillary carcinoma was observed in the third to fifth decades, while follicular and anaplastic carcinomas were more common after the fourth decade.