Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise-induced arterial hypoxemia.

J A Dempsey1, P D Wagner

  • 1John Rankin Laboratory of Pulmonary Medicine, Department of Preventive Medicine, University of Wisconsin-Madison, Madison, Wisconsin 53705, USA. jdempsey@facstaff.wisc.edu

Journal of Applied Physiology (Bethesda, Md. : 1985)
|December 22, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Central sleep apnea.

Comprehensive Physiology·2013
Same author

Impact factor and its role in academic promotion.

The European respiratory journal·2009
Same author

Exercise-induced respiratory muscle work: effects on blood flow, fatigue and performance.

Advances in experimental medicine and biology·2007
Same author

The apneic threshold during non-REM sleep in dogs: sensitivity of carotid body vs. central chemoreceptors.

Journal of applied physiology (Bethesda, Md. : 1985)·2007
Same author

Response time and sensitivity of the ventilatory response to CO2 in unanesthetized intact dogs: central vs. peripheral chemoreceptors.

Journal of applied physiology (Bethesda, Md. : 1985)·2005
Same author

Repeat exercise normalizes the gas-exchange impairment induced by a previous exercise bout in asthmatic subjects.

Journal of applied physiology (Bethesda, Md. : 1985)·2005
Same journal

Thoroughbred horses susceptible to Recurrent Exertional Rhabdomyolysis have elevated skeletal muscle mitochondrial capacities.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Change in Neutrophil-to-Lymphocyte Ratio after acute and chronic exercise: A Systematic Review and Meta-Analysis.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Ankylosing spondylitis and muscle sympathetic nerve activity: a case study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Intracranial vasomotor and blood flow responses to light intensity aerobic exercise in young adults: a 4D flow MRI study.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Comparative assessments of the COSMED adaptive mixing chamber vs. breath-by-breath methods for oxygen uptake measurements in recreationally active adults.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same journal

Can we assess exercise metabolism from skin? Metabolomic profiles in skin dialysate collected during exercise.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
See all related articles

Exercise-induced arterial hypoxemia (EIAH) affects fit individuals, causing low oxygen levels during exercise. This review defines EIAH severity and explores its complex causes and impact on performance.

Area of Science:

  • Physiology
  • Sports Medicine
  • Respiratory Medicine

Background:

  • Exercise-induced arterial hypoxemia (EIAH) is increasingly recognized in healthy, fit individuals.
  • Understanding EIAH mechanisms and performance consequences is crucial.

Purpose of the Study:

  • To define EIAH and its severity levels.
  • To critically analyze current knowledge of EIAH mechanisms.
  • To assess the impact of EIAH on exercise performance.

Main Methods:

  • Review of existing literature on EIAH.
  • Analysis of factors contributing to EIAH, including alveolar-to-arterial PO2 difference (A-a DO2) and hyperventilation.
  • Examination of physiological constraints like expiratory flow limitation and V/Q mismatch.

Related Experiment Videos

Main Results:

  • Proposed definitions for mild (93-95% SpO2), moderate (88-93% SpO2), and severe (<88% SpO2) EIAH.
  • Common contributors to EIAH include excessive A-a DO2 and inadequate hyperventilation.
  • Expiratory flow limitation, V/Q maldistribution, and diffusion limitation play significant roles.

Conclusions:

  • Mechanisms of diffusion limitation and V/Q maldistribution in EIAH remain unclear.
  • Inadequate hyperventilation may stem from feedback inhibition, but requires further investigation.
  • EIAH negatively impacts maximal oxygen uptake, though the precise limiting organ system is unidentified.