[Analysis of immunological indices of occupational sensibilization to tylosin]

The authors studied sensibilization to antibiotic Tilosine and determined several immunologic parameters in Tilosine production workers, searching for criteria of the sensibilization's occupational etiology. The results prove that skin allergic reactivity, antibodies production and lymphocytes proliferation response are diagnostic for immune changes in workers exposed to occupational allergens and useful for assessing risk of allergic disorders.