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09:54
Lentiviral Vector-mediated Gene Therapy of Hepatocytes Ex Vivo for Autologous Transplantation in Swine
Published on: November 4, 2018
Biotechnologies and liver diseases.
1Department of Surgery, Royal Free Hospital School of Medicine, London.
Forum (Genoa, Italy)
|December 23, 1999
Summary
Viral hepatitis poses a significant European health challenge. Economic evaluations of hepatitis A and B vaccines are discussed, alongside the critical need for hepatitis C vaccines and improved treatments.
Area of Science:
- Public Health
- Virology
- Hepatology
Background:
- Viral hepatitis represents a substantial public health concern across Europe.
- Current vaccination strategies and antiviral therapies for hepatitis B and C are discussed.
- The limitations of liver transplantation and artificial liver support are highlighted.
Purpose of the Study:
- To survey viral hepatitis as a European problem.
- To discuss the economic implications of hepatitis A and B vaccination programs.
- To emphasize the need for hepatitis C vaccines and improved treatments.
Main Methods:
- Economic analysis of vaccination programs.
- Review of current antiviral therapies.
- Discussion of liver transplantation and artificial liver support limitations.
Main Results:
- Vaccination against hepatitis A and B has significant economic implications for infant and adolescent programs.
- Antiviral therapy for hepatitis B and C remains unsatisfactory.
- Donor shortage limits liver transplantation, necessitating research into artificial liver support.
Conclusions:
- There is an urgent need for a hepatitis C vaccine.
- Current antiviral treatments for hepatitis B and C are inadequate.
- Increased research into artificial liver support methods is crucial due to donor shortages for liver transplantation.
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