Related Experiment Videos
Transdermal histamine in multiple sclerosis: part one -- clinical experience.
Alternative Medicine Review : a Journal of Clinical Therapeutic
|December 23, 1999
Summary
Transdermal histamine cream shows promise for multiple sclerosis (MS) symptom relief. Preliminary data indicates significant improvements in strength, balance, bladder control, fatigue, daily activities, and cognition for many patients.
Area of Science:
- Neuroscience
- Immunology
- Dermatology
Background:
- Histamine has a historical therapeutic role in various diseases.
- Transdermal histamine application has recently emerged for multiple sclerosis (MS) symptom management.
- Both relapsing-remitting and progressive MS forms have shown potential benefit.
Purpose of the Study:
- To summarize preliminary clinical experiences with transdermal histamine for MS patients.
- To assess the efficacy and patient-reported outcomes of transdermal histamine cream.
- To explore potential mechanisms of action for transdermal histamine in MS.
Main Methods:
- A cohort of 55 patients with multiple sclerosis used transdermal histamine cream.
- Patient-reported outcomes were collected focusing on functional improvements.
- Symptom amelioration was tracked over a three-month period.
Main Results:
- 67% of patients experienced improvements in at least one functional area.
- Improvements were noted in extremity strength, balance, bladder control, fatigue, activities of daily living, and cognitive function.
- One-third of patients reported improvements in three or more areas, sustained up to three months.
Conclusions:
- Transdermal histamine cream appears to be a potentially effective treatment for multiple sclerosis symptoms.
- The treatment demonstrated broad efficacy across multiple domains of functioning in MS patients.
- Further investigation into the proposed mechanisms of action is warranted.