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Related Experiment Videos

Millennium bugs.

J Davies1

  • 1TerraGen Discovery Inc. and Dept of Microbiology and Immunology, University of British Columbia, Vancouver, Canada. jed@interchange.ubc.ca

Trends in Cell Biology
|December 28, 1999
PubMed
Summary
This summary is machine-generated.

Microbiology research is advancing, but most microbes remain uncultured. Genomic sequencing will drive new discoveries about their roles in life and evolution.

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Area of Science:

  • Microbiology
  • Genomics
  • Evolutionary Biology

Background:

  • Microbes are essential for all life on Earth.
  • Less than 1% of microorganisms are currently culturable in laboratories.
  • Over a century of research has only scratched the surface of microbial life.

Purpose of the Study:

  • To highlight the vast unexplored potential of microbiology.
  • To emphasize the role of complete bacterial genome sequencing in advancing research.
  • To outline future research directions in understanding microbial roles.

Main Methods:

  • Analysis of current limitations in microbial cultivation.
  • Anticipation of research enabled by bacterial genome sequencing.
  • Review of the significance of microbial life in evolutionary processes.

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Main Results:

  • The vast majority of microbial life remains uncharacterized.
  • Complete genome sequences are poised to unlock new research avenues.
  • Understanding microbial roles is critical for academic, medical, and industrial applications.

Conclusions:

  • Microbiology faces significant intellectual challenges but holds immense promise.
  • Bacterial genome sequencing will be a key driver for future microbial research.
  • Elucidating microbial roles is crucial for understanding evolution and biosphere maintenance.