Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vertebrate endoderm development.

J M Wells1, D A Melton

  • 1Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA. wells@biohp.harvard.edu

Annual Review of Cell and Developmental Biology
|December 28, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Properties of New Partially Crystallized Lithium Disilicate CAD-CAM Materials.

Operative dentistry·2025
Same author

Oral Health, Inflammation, and Cardiometabolic Factors in the VA Million Veteran Program.

JDR clinical and translational research·2024
Same author

Expression of the Xhox3 Homeobox Protein in Xenopus Embryos: Blocking Its Early Function Suggests the Requirement of Xhox3 for Normal Posterior Development: (axial pattern/central nervous system/embryonic mesoderm/homeobox gene/Xenopus laevis).

Development, growth & differentiation·2023
Same author

FACTORS AFFECTING THE KINETICS OF INTRA-AND EXTRACELLULAR CADMIUM UPTAKE BY THE MOSS RHYTIDIADELPHUS SQUARROSUS.

The New phytologist·2021
Same author

Ionic control of intracellular and extracellular Cd uptake by the moss Rhytidiadelphus squarrosus (Hedw.) Warnst.

The New phytologist·2021
Same author

Effect of temperature on wood decay and translocation of soil-derived phosphorus in mycelial cord systems.

The New phytologist·2021
Same journal

Hidden Messages in Extracellular Vesicles: Cross-Kingdom RNA Communication in Plant and Microbe Interactions.

Annual review of cell and developmental biology·2026
Same journal

mRNA-Scaffolded Cytoplasmic Compartments.

Annual review of cell and developmental biology·2026
Same journal

Developmental Programming of Human Kidney Function.

Annual review of cell and developmental biology·2026
Same journal

The Translation of Genetic Information in Neurodevelopment.

Annual review of cell and developmental biology·2026
Same journal

The Origin and Early Evolution of Fungi: Challenges, Inferences, and Principles.

Annual review of cell and developmental biology·2026
Same journal

Interstitial Spaces: A Basolateral Source of Structure and Signals.

Annual review of cell and developmental biology·2026
See all related articles

This review details endoderm development, covering its formation, gut tube morphogenesis, organ budding, and cell differentiation. It explores mechanisms specifying endoderm into diverse respiratory and gastrointestinal cell types.

Area of Science:

  • Developmental Biology
  • Cell Biology
  • Organogenesis

Background:

  • Endoderm is a primary germ layer crucial for alimentary tract organ development.
  • Understanding endoderm formation is key to comprehending gastrointestinal and respiratory system development.

Purpose of the Study:

  • To review the fundamental steps in endodermal organ formation.
  • To discuss regulatory mechanisms governing endoderm specification into diverse cell types.

Main Methods:

  • Literature review of endoderm development.
  • Analysis of key stages: gastrulation, gut tube morphogenesis, organ budding, and cell differentiation.

Main Results:

  • Endodermal organ formation is described in four stages: initial formation, tube morphogenesis, domain budding, and cell differentiation.

Related Experiment Videos

  • Mechanisms regulating the specification of undifferentiated endoderm into specialized cell types are discussed.

    • Conclusions:

    • The review provides a framework for understanding endodermal organogenesis.
    • Further research into regulatory mechanisms can illuminate developmental processes and potential therapeutic targets.