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Synthesis of steroidal nitrosoureas with antitumor activity

H Y Lam, A Begleiter, G J Goldenberg

Journal of Medicinal Chemistry

|February 1, 1979

Abstract:

Four steroidal nitrosoureas with structures which may permit specific binding to estrogen receptor were synthesized. Inhibitory activity was observed against the growth of the DMBA-induced transplantable rat mammary tumor 13762.

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