Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Plasma free, phospholipid-bound and urinary free choline all decrease during a marathon run and may be associated

A L Buchman¹, D Jenden, M Roch

¹Division of Gastroenterology, Hepatology and Nutrition, University of Texas Houston Health Science Center, USA.

Journal of the American College of Nutrition

|December 29, 1999

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Risk-adapted intensification therapy in high-risk prostate cancer: how relevant is the role of radiation dose.

Radiation oncology (London, England)·2025

Same author

Dosimetric impact of rectum and bladder anatomy and intrafractional prostate motion on hypofractionated prostate radiation therapy.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021

Same author

Impact of rectum and bladder anatomy in intrafractional prostate motion during hypofractionated radiation therapy.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2018

Same author

Characterization and simulation of noise in PET images reconstructed with OSEM: Development of a method for the generation of synthetic images.

Revista espanola de medicina nuclear e imagen molecular·2018

Same author

Reduced late urinary toxicity with high-dose intensity-modulated radiotherapy using intra-prostate fiducial markers for localized prostate cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2017

Same author

Value of the preservation of an osseous mandibular rim with a fibula free flap reconstruction.

Revue de laryngologie - otologie - rhinologie·2016

Same journal

Response to Commentary.

Journal of the American College of Nutrition·2021

Same journal

Risk of Osteoarthritis is Positively Associated with Vitamin D Status, but Not Bone Mineral Density, in Older Adults in the United States.

Journal of the American College of Nutrition·2021

Same journal

Nutrient Intake and Muscle Measures in Geriatric Outpatients.

Journal of the American College of Nutrition·2021

Same journal

Analyzing Blood Pressure Ascent during Aging in Non-Diabetics: Focusing on Links to Insulin Resistance and Body Fat Mass.

Journal of the American College of Nutrition·2021

Same journal

Effect of a Free-Living Ketogenic Diet on Feasibility, Satiety, Body Composition, and Metabolic Health in Women: The Grading Level of Optimal Carbohydrate for Women (GLOW) Study.

Journal of the American College of Nutrition·2021

Same journal

The Prophylactic Activity of <i>Punica granatum</i> L. mesocarp Protects Preadipocytes against Ribosylated BSA-Induced Toxicity.

Journal of the American College of Nutrition·2021

See all related articles

Marathon running significantly decreases plasma and urinary choline levels, indicating accelerated metabolism or tissue uptake. This change in choline status did not directly correlate with marathon performance.

Area of Science:

Biochemistry
Sports Science
Human Physiology

Background:

Previous research indicates plasma free choline declines during prolonged endurance running.
Choline is essential for various physiological functions, including cell membrane integrity and neurotransmitter synthesis.

Purpose of the Study:

To investigate changes in body choline status during marathon running.
To determine if altered choline levels affect marathon performance.

Main Methods:

Studied 23 marathon runners before and after a marathon race.
Collected fasting blood and urine samples at multiple time points.
Assessed performance using predicted versus actual finish times.

Main Results:

Related Experiment Videos

Plasma free and phospholipid-bound choline, along with urinary free choline, decreased immediately post-race.
Choline levels generally rebounded after 48 hours but remained below baseline.
A decrease in urinary free choline correlated with a poorer predicted-to-actual finish time ratio.

Conclusions:

Decreased choline status suggests increased metabolism or tissue uptake, not reduced liver release.
The impact of choline supplementation on endurance running performance warrants further research.