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Synthesis of some pyridine ribosides and their biological activity
A M Attia1, H A Mansour, A A Almehdi
1Department of Chemistry, Faculty of Education, Tanta University, Kafr El- Sheikh, Egypt.
Nucleosides & Nucleotides
|January 5, 2000
Abstract:
A synthesis of 1-(beta-D-ribofuranosyl)-pyridin-2-thiones via reaction of 3-cyanopyridin-2(1H)-thiones with 2,3,5-tri-O-benzoyl-D-ribofuranosyl bromide under basic conditions, followed by hydrolysis with methanolic ammonia is reported.