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Synthesis and hybridization properties of oligonucleotides containing 6-membered azasugar nucleotides
Bioorganic & Medicinal Chemistry Letters
|January 5, 2000
Abstract:
A modified nucleoside was synthesized with adenine and a 6-membered azasugar, and it was converted to the phosphoramidite which was used for the incorporation into oligonucleotides. The hybridization properties of the modified oligonucleotides with DNA and RNA were studied.