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Updated: Aug 2, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Nasal sinus metastasis of renal carcinoma. A case report]
V Montoro Martínez1, M López Vilas, M Gurri Freixa
1Servicio de ORL, Hospital de la Santa Creu i Sant Pau, Barcelona, 08025, España.
Abstract:
Renal cell carcinoma is the primary neoplasm which most frequently metastasizes in the nasosinusal region. We present a case of a 51-year-old man who was nephrectomized for a renal cell carcinoma. A year later, he presented a left nasosinusal lesion. The biopsy was conclusive for renal cell metastasis. A paralateronasal and bicoronal approach was used. Currently, 6 years later the patient is free of local disease, but he presents cutaneous metastasis. Renal cell nasosinusal metastasis is found in a context of disseminated disease. Symptoms are unspecific, but the epistaxis constitutes the most common sign due to the significant vascularizations of the tumor. Definitive diagnosis is obtained from the biopsy of the tumor. TC and RM illustrated the lesion's extension and involvement of adjacent structures. Prognosis is poor. The survival rate fluctuates between 15-30% at 5 years. Surgery is the elective treatment but should be considered on an individual basis.
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