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Complete response to topotecan of recurrent fallopian tube carcinoma
1Department of Obstetrics and Gynecology, Jefferson Medical College, Philadelphia, Pennsylvania, 19107, USA.
Gynecologic Oncology
|January 6, 2000
Abstract
Objective:
To describe the first complete response of recurrent Fallopian tube carcinoma to topotecan.
Methods:
A patient with recurrent Fallopian tube carcinoma previously treated with paclitaxel (Taxol) and carboplatin is described.
Results:
This patient demonstrated a complete clinical response to topotecan. Radiographic and CA-125 measurements were used to determine response. Response was noted after four cycles and a complete response demonstrated after six treatments.
Conclusion:
Topotecan appears active in recurrent Fallopian tube carcinoma.