Related Experiment Videos
Spontaneous spondylodiscitis caused by Klebsiella pneumoniae
C Kouroussis1, V Georgoulias, J Souglakos
1University of Crete, Division of Medicine, Greece.
Abstract:
A rare case of spontaneous spondylodiscitis caused by Klebsiella pneumoniae in a 55-year-old man who presented with thoracolumbar pain is described. Increased erythrocyte sedimentation rate and C-reactive protein level were pertinent laboratory findings. Computed tomography revealed a paravertebral mass and destruction of the 10th and 11th vertebrae. Magnetic resonance imaging (MRI) showed spondylodiscitis in the same area. Culture of a biopsy sample from the mass grew Klebsiella pneumoniae, while histological examination confirmed the inflammation. A combination of ceftazidime, amikacin and ciprofloxacin resulted in disappearance of the pain. Two months later, MRI showed substantial improvement of the lesions.
Insights
This case study details a rare instance of spontaneous spondylodiscitis caused by Klebsiella pneumoniae in a 55-year-old man. Prompt antibiotic treatment led to significant clinical improvement and lesion resolution.
Area of Science:
- Infectious Diseases
- Spinal Surgery
- Radiology
Background:
- Spontaneous spondylodiscitis is an uncommon spinal infection.
- Klebsiella pneumoniae is a Gram-negative bacterium that can cause serious infections.
Observation:
- A 55-year-old man presented with thoracolumbar pain and elevated inflammatory markers.
- Imaging revealed a paravertebral mass and vertebral destruction at T10-T11.
- Biopsy confirmed Klebsiella pneumoniae infection and inflammation.
Findings:
- Successful treatment with a combination of ceftazidime, amikacin, and ciprofloxacin.
- Complete resolution of pain and substantial MRI-confirmed improvement of spinal lesions within two months.
Implications:
- Highlights the importance of considering Klebsiella pneumoniae in spontaneous spondylodiscitis.
- Demonstrates effective antibiotic therapy for this rare condition.
- Emphasizes the role of advanced imaging in diagnosis and monitoring treatment response.