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Neuroactive neurosteroids: dehydroepiandrosterone (DHEA) and DHEA sulphate
1College de France et Institut National de la Santé et de la Recherche Médicale, Le Kremlin-Bicêtre, France. baulieu@kb.inserm.fr
Acta Paediatrica (Oslo, Norway : 1992). Supplement
|January 8, 2000
Abstract:
Dehydroepiandrosterone (DHEA) and its sulphate ester (DHEAS) are neuroactive and are both imported into the brain from the circulation and produced in the nervous system. These neurosteroids have neurotrophic and excitatory effects, and further study is needed to delineate their physiological and pathological functions.