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Lens cytoskeleton and transparency: a model

J I Clark1, H Matsushima, L L David

  • 1Department of Biological Structure, University of Washington, School of Medicine, Seattle 98195-7420, USA. clarkji@u.washington.edu

Eye (London, England)
|January 11, 2000
PubMed

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The cytoskeletal architecture can be studied using different microscopic and biochemical techniques. Electron microscopy was instrumental in discovering the cytoskeletal architecture around the 1960s, which allowed obtaining structural information at a high-resolution level. However, the sample preparation procedure often limits this ability in biological samples. Several protocols have been developed over the years to optimize sample preparation. In one of the protocols known as rotary...