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Potential involvement of post-translational modifications as a mechanism modulating selective proteolysis after
M Imschenetzky1, M Puchi, V Morin
1Department of Molecular Biology, Universidad de Concepción, Casilla 160-C, Concepción, Chile. mimschen@udec.cl
Journal of Cellular Biochemistry
|January 11, 2000
Abstract:
The role of proteolysis during fertilization has been investigated only to a very limited extent as compared with its role on the control of cell cycle progression. In this report, we discuss briefly the proteases involved in fertilization, their relevance in the egg-sperm interaction and in the chromatin remodeling that occurs before the reestablishment of the diploid condition of the zygote. We further emphasize how the post-translational modifications of target proteins modulate these proteolytic events. J. Cell. Biochem. Suppls. 32/33:149-157, 1999.