Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fetal interventions for obstructive uropathy.

D S Walsh1, M P Johnson

  • 1Center for Fetal Diagnosis and Treatment, the Children's Hospital of Philadelphia, PA 19104, USA.

Seminars in Perinatology
|January 12, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Temporal complexity of LVV-hemorphin-7 allosterism at the angiotensin II type 1 receptor assessed using entropy-based approaches.

Computational and structural biotechnology journal·2025
Same author

Radiation dose reduction in pediatric computed tomography (CT) using deep convolutional neural network denoising.

Clinical radiology·2024
Same author

Diffuse Calvarial Hyperostosis and Spontaneous Intracranial Hypotension: A Case-Control Study.

AJNR. American journal of neuroradiology·2022
Same author

Reply.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2020
Same author

In vitro fertilization analysis of squirrel monkey oocytes produced by various follicular induction regimens and the incidence of triploidy.

American journal of primatology·2020
Same author

Evaluation of Lower-Dose Spiral Head CT for Detection of Intracranial Findings Causing Neurologic Deficits.

AJNR. American journal of neuroradiology·2019
Same journal

Congenital cytomegalovirus: Screening strategies and diagnostic challenges.

Seminars in perinatology·2026
Same journal

The society for neonatal nutrition and lifelong health: Building science and translating research to inform neonatal nutritional care.

Seminars in perinatology·2026
Same journal

Enteral nutrition to optimize health and neurodevelopmental outcomes in very preterm infants.

Seminars in perinatology·2026
Same journal

Standardizing outcome measures in preterm infant nutrition research: Use of anthropometry and body composition in the neonatal intensive care unit.

Seminars in perinatology·2026
Same journal

A dilemma of parental inclusion? Parent perspectives of NICU feeding practices and neonatal nutritional research.

Seminars in perinatology·2026
Same journal

Maternal diet and nutritional status during pregnancy and lactation: a review of implications on milk composition and lactation outcomes.

Seminars in perinatology·2026
See all related articles

Fetal therapy for obstructive uropathy shows promise in preventing urinary tract damage and improving lung development by draining urine in utero. Further research is needed to confirm benefits in humans.

Area of Science:

  • Neonatal medicine
  • Fetal surgery
  • Pediatric urology

Background:

  • Obstructive uropathy is a major cause of death and illness in infants.
  • Diagnosis is often made via ultrasound in the second trimester.
  • Current postnatal management has limitations.

Purpose of the Study:

  • To review the diagnosis, techniques, and outcomes of fetal treatment for obstructive uropathy.
  • To highlight the potential of in utero therapy to improve neonatal outcomes.
  • To discuss the role of diagnostic standardization and future research in patient selection.

Main Methods:

  • Review of existing literature on fetal vesicoamniotic shunting.
  • Analysis of diagnostic evaluation methods for obstructive uropathy.

Related Experiment Videos

  • Examination of outcomes from animal models and preliminary human studies.

    • Main Results:

    • In utero intervention may prevent progressive renal damage and oligohydramnios-related lung issues.
    • Standardized diagnosis improves patient selection for fetal shunting.
    • Animal studies suggest benefits, but large human trials are pending.

    Conclusions:

    • Fetal treatment for obstructive uropathy offers a promising approach to improve outcomes.
    • Refined patient selection and further research into growth factors are crucial.
    • Standardized diagnosis and technique are key to successful fetal vesicoamniotic shunting.