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Separation of enantiomers on anion exchangers modified with heparin in liquid chromatography
Safni1, N Ito, T Takeuchi
1Department of Chemistry, Faculty of Engineering, Gifu University, Japan.
Journal of Chromatography. A
|January 12, 2000
Abstract:
The separation of enantiomers of chloroquine and other amine derivatives has been investigated by liquid chromatography using anion exchangers modified with heparin as the stationary phase. Modification and mobile phase conditions affected the separation of analytes. Separation of the chloroquine enantiomers could be achieved by using a buffer solution containing acetonitrile as the mobile phase.