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Malignant phyllodes tumor of the prostate
1Department of Pathology, Chonnam National University Medical School and Research Institute of Medical Sciences, Kwangju, Korea.
Pathology International
|January 13, 2000
Summary
Phyllodes tumors of the prostate are rare. This case highlights a malignant variant with aggressive features and rapid recurrence after surgery.
Area of Science:
- Uropathology
- Oncology
Background:
- Phyllodes tumors are rare neoplasms typically found in the breast.
- Prostate involvement by phyllodes tumors is exceptionally uncommon.
Observation:
- A 57-year-old male presented with a year of urinary retention.
- A prostate tumor exhibited epithelial positivity for prostate-specific antigen.
- Stromal cells displayed nuclear atypia and high mitotic activity.
Findings:
- The tumor invaded the urinary bladder and rectum.
- Rapid postoperative growth confirmed its malignant nature.
- Morphological and immunohistochemical features were consistent with malignant phyllodes tumor.
Implications:
- This case expands the understanding of rare prostate malignancies.
- Highlights the importance of thorough histopathological evaluation for accurate diagnosis.
- Suggests aggressive management may be required for malignant phyllodes tumors of the prostate.