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Geographic studies of pediatric cancer near hazardous waste sites
1North Carolina Central Cancer Registry, Chapel Hill, USA.
Insights
This study investigated pediatric cancer rates near hazardous waste sites in North Carolina. No overall increase was found, but two ZIP codes showed higher cancer incidence, warranting further environmental health research.
Area of Science:
- Environmental epidemiology
- Pediatric oncology
- Geographic Information Systems (GIS)
Background:
- Concerns exist regarding potential health impacts of National Priorities List (NPL) hazardous-waste sites.
- Assessing cancer incidence in pediatric populations near such sites requires precise spatial analysis.
Purpose of the Study:
- To determine if pediatric cancer incidence is elevated in North Carolina counties and ZIP codes with NPL hazardous-waste sites.
- To explore the utility of GIS in mapping and analyzing environmental health data.
Main Methods:
- Utilized geographic information systems (GIS) to map pediatric cancer cases (ages 0-17) from 1990-1993.
- Analyzed cancer incidence rates in relation to NPL hazardous-waste site locations at county and ZIP-code levels.
- Investigated proximity of cancer cases to hazardous-waste sites using a 1.6-km buffer zone.
Main Results:
- No statistically significant elevation in pediatric cancer incidence was observed at the county level.
- Two specific ZIP-code areas exhibited statistically significant increases in cancer incidence (p < .05).
- Only three mapped pediatric cancer cases were within 1.6 km of an NPL site, and these were not in the identified high-incidence ZIP codes.
Conclusions:
- The study found no widespread elevated pediatric cancer rates near hazardous-waste sites in North Carolina.
- Identified localized ZIP-code areas with increased incidence suggest potential environmental factors requiring further investigation.
- The exploratory nature of this research highlights the need for more in-depth environmental health studies and specific exposure investigations.
Abstract:
The incidence of pediatric (i.e., 0-17 y of age) cancers in North Carolina was studied for the years 1990-1993 in counties and ZIP-code areas that contained a National Priorities List hazardous-waste site. We analyzed the areas to determine if there was an excess incidence of cancer among the pediatric population. We used geographic information systems technology to address-match and map the cancer cases, along with county and National Priorities List hazardous waste-site location. No significantly elevated cancer incidence rates were found at the county level. Two ZIP-code areas had statistically significant elevations in cancer incidence (p < .05). Only 3 of the cancer cases we mapped resided within a 1.6-km (1 mi) buffer zone of a National Priorities List hazardous-waste site. These 3 cases were not in the ZIP-code areas that had increased incidence rates. The small numerators throughout the study led us to question the accuracy of the assessment of underlying rates. The general capabilities of the geographic information systems, as well as advantages and limitations of the system, are discussed. As an exploratory study, this study serves as a springboard into more in-depth environmental-health hypotheses and more-specific investigations of point sources of hazardous exposures.
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