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Cloning and characterization of a Drosophila melanogaster cDNA encoding a glutamate transporter
T Kawano1, K Takuwa, H Kuniyoshi
1Department of Biological and Environmental Chemistry, Faculty of Agriculture, Tottori University, Japan. kawano@muses.tottori-u.ac.jp
Bioscience, Biotechnology, and Biochemistry
|January 15, 2000
Abstract:
A Drosophila cDNA encoding a glutamate transporter was cloned and examined. The predicted protein (479 amino acid residues) shows significant sequence identity with mammalian counterparts. The protein expressed in Xenopus oocytes had a glutamate transport activity. Northern blot analysis showed that the transcript increased in amount developmentally. This expression pattern is different from those of Drosophila glutamate receptors.