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Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
Published on: March 19, 2019
Candida albicans: an opportunistic threat to critically ill low birth weight infants
L Witek-Janusek1, C Cusack, H L Mathews
1Department of Maternal Child Health Nursing, Loyola University of Chicago, USA.
Abstract:
Major advances in the management of critically ill low birth weight (LBW) infants have increased their survival. Yet the clinical course of these infants is complicated by the emergence of opportunistic microbial pathogens. Most importantly, serious infections from opportunistic fungi, such as Candida albicans, have produced systemic disease in vulnerable LBW infants. Invasive C. albicans infection is generally difficult to manage and is associated with high morbidity and mortality. Because the infection has an insidious and rapid course, the critical care nurse and advanced practice nurse need to provide key prevention and early treatment measures.
Insights
Advances in critical care improve survival for low birth weight (LBW) infants, but opportunistic fungal infections like Candida albicans pose significant risks. Early detection and intervention are crucial for preventing severe outcomes in these vulnerable newborns.
Area of Science:
- Neonatal intensive care
- Infectious diseases
- Mycology
Background:
- Critically ill low birth weight (LBW) infants face increased susceptibility to opportunistic pathogens.
- Systemic fungal infections, particularly invasive Candida albicans, present a severe threat to LBW infants.
- High morbidity and mortality rates are associated with invasive candidiasis in this population.
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