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Expression and cellular localization of the Toucan protein during Drosophila oogenesis
M Grammont1, G Berson, B Dastugue
1Institut National de la Santé et de la Recherche Médicale U384, Laboratoire de Biochimie, UFR Médecine, 28, place Henri Dunant, 63001, Clermont-Ferrand, France.
Mechanisms of Development
|January 21, 2000
Abstract:
The toucan (toc) gene is required in the germline for somatic cell patterning during Drosophila oogenesis. To better understand the function of toc, we performed a detailed analysis of the distribution of the Toucan protein during oogenesis. Toc expression is restricted to the germline cells and shows a dynamic distribution pattern throughout follicle development. Mislocalization of the Toc protein in mutant follicles in which the microtubule network is altered indicates that microtubules play a role in Toc localization during oogenesis.