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Related Experiment Videos

Angina pectoris in severe aortic stenosis.

G Dangas1, S Khan, B H Curry

  • 1Mount Sinai Hospital, Cardiac Catheterization Laboratory, New York, NY 10029, USA.

Cardiology
|January 21, 2000
PubMed
Summary

In very elderly patients with severe aortic stenosis, angina pectoris strongly predicts coronary artery disease. Its absence suggests no significant coronary artery disease, aiding treatment decisions.

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Area of Science:

  • Cardiology
  • Geriatric Medicine

Background:

  • Severe aortic stenosis (AS) often coexists with coronary artery disease (CAD).
  • Predicting CAD in very elderly patients undergoing AS treatment is clinically important.

Purpose of the Study:

  • To evaluate angina pectoris as a predictor of significant CAD in patients aged ≥70 years with severe AS.
  • To assess the diagnostic value of angina in this specific high-risk population.

Main Methods:

  • Retrospective analysis of 90 patients (age ≥70) referred for balloon aortic valvuloplasty.
  • Coronary angiography performed before valvular intervention.
  • Patients categorized based on presence or absence of angina pectoris.

Main Results:

  • 78% of patients with angina had obstructive CAD (>50% stenosis) versus 17% without angina (p < 0.01).

Related Experiment Videos

  • Angina pectoris demonstrated 78% sensitivity and 82% specificity for obstructive CAD.
  • Absence of angina was highly predictive of the absence of obstructive CAD.

    • Conclusions:

    • Angina pectoris is a significant predictor of obstructive CAD in very elderly patients with severe AS.
    • The absence of angina can reliably rule out significant CAD in this population.
    • Clinical decisions regarding AS management in the elderly should not be delayed by the need for routine coronary angiography.