Adult ADHD Medications and Their Cardiovascular Implications.
1Division of Cardiology, Saint Luke's University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USA.
Central nervous system stimulants treat attention-deficit/hyperactivity disorder (ADHD) but long-term cardiovascular effects require further study. This case highlights acute myocardial infarction (AMI) risk in adults with ADHD on stimulant medication.
Area of Science:
- Neuroscience
- Cardiology
- Pharmacology
Background:
- Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder.
- Central nervous system (CNS) stimulants are a primary treatment for ADHD.
- Concerns exist regarding the long-term cardiovascular safety of CNS stimulants in adults.
Purpose of the Study:
- To investigate the cardiovascular safety of CNS stimulants in adult ADHD patients.
- To explore the association between stimulant use and adverse cardiovascular events.
- To present a case of acute myocardial infarction (AMI) in an adult ADHD patient on Adderall.
Main Methods:
- Literature review on cardiovascular effects of CNS stimulants in adult ADHD.
- Case report of AMI in an adult treated with mixed amphetamine salts (Adderall).
Main Results:
- Cardiovascular effects of ADHD medications primarily include elevated heart rate and blood pressure.
- Etiology of rare events like AMI, arrhythmia, and cardiomyopathy remains less understood.
- A unique case of AMI in an adult ADHD patient on Adderall is presented.
Conclusions:
- Further research is needed to understand the long-term cardiovascular risks of CNS stimulants in adults with ADHD.
- The case report underscores the potential for serious cardiovascular events, including AMI.
- Cardiovascular safety monitoring is crucial for adults with ADHD on stimulant therapy.
More Related Videos
13:09Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
Published on: April 1, 2018
05:48The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
Published on: June 12, 2020
Related Concept Videos
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Adrenergic Antagonists: Pharmacological Actions of β-Receptor Blockers
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers
Adrenergic Agonists: Indirect-Acting Agents
One mechanism involves depleting stored catecholamines by displacing them from synaptic vesicles. These agents, known as "displacers," are transported into vesicles at the expense of noradrenaline. Examples include amphetamine and tyramine, which lack a catechol moiety, resulting in prolonged action, improved oral...
Cardiovascular Drugs: Classification based on Therapeutic Indications
