[Exhaled nitric oxide as marker of inflammation in children with asthma]

The nitric oxide is a reactive gas that is produced of endogenous way by enzymes nitric oxide sintetase. Exist a great nitric oxide production induced by the isoforms of the enzyme nitric oxide sintetase, that gives as a result the products training citotoxic, they are important mediating of the defence mechanisms and of normal inflammatory response. The nitric oxide can be detected in the air exhaled in human, their concentrations are increased in patient with asthma, and after the exposition to allergens. The measurement of the exhaled nitric oxide is effected by simple methods, not invasive, to value the degree of inflammation of the air route and response to the treatment with steroids in pediatric patients.