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Paroxysmal tonic upgaze: physiopathological considerations in three additional cases
A Spalice1, P Parisi, P Iannetti
1Pediatric Department, University La Sapienza, Rome, Italy.
Journal of Child Neurology
|January 21, 2000
Summary
Paroxysmal tonic upgaze in children may indicate broader neurological issues, not just an eye movement disorder. Early detection and identifying mesencephalic gray matter involvement are crucial for understanding this condition.
Area of Science:
- Pediatric Neurology
- Ophthalmology
- Neuroscience
Background:
- Paroxysmal tonic upgaze (PTU) is often considered a benign childhood syndrome of abnormal eye movements.
- Previous reports noted associated neurological abnormalities in some children with PTU.
- Recent theories suggest PTU might be a heterogeneous syndrome or an early sign of wider neurological dysfunction.