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[Conjugates of polyacrylamide with oligonucleotides and their mimetics for diagnostic purposes]
V A Efimov1, O G Chakhmakhcheva
1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia. eva@ibch.siobc.ras.ru
Bioorganicheskaia Khimiia
|January 25, 2000
Abstract:
Approaches to preparing acrylamide and polyacrylamide conjugates with oligonucleotides and some peptide nucleic acid-related DNA mimics are considered. Their physicochemical properties and application to the nucleic acid analysis are discussed.