Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary resection for metastatic osteogenic sarcoma.

P K Spanos, W S Payne, J C Ivins

    The Journal of Bone and Joint Surgery. American Volume
    |July 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    EXPERIMENTAL MANIPULATION OF ALTERNATIVE PATHWAYS OF DIFFERENTIATION IN CULTURES OF EMBRYONIC CHICK NEURAL RETINA.

    Development, growth & differentiation·2023
    Same author

    Treating hummingbirds as feathered bees: a case of ethological cross-pollination.

    Biology letters·2017
    Same author

    Chondroblastoma.

    Orthopedics·2014
    Same author

    Chordoma of the sacrum.

    Orthopedics·2014
    Same author

    Mayo clinic tumor rounds.

    Orthopedics·2014
    Same author

    Extraabdominal desmoid tumor.

    Orthopedics·2014

    Pulmonary resection for metastatic osteosarcoma offers survival benefits, particularly for young males with lower extremity primary lesions. Long-term survival is linked to a tumor-free interval over two years and limited metastatic sites.

    Area of Science:

    • Oncology
    • Thoracic Surgery
    • Orthopedic Oncology

    Background:

    • Osteosarcoma commonly metastasizes to the lungs.
    • Surgical resection of pulmonary metastases is a potential treatment modality.
    • Identifying prognostic factors for survival is crucial.

    Purpose of the Study:

    • To evaluate the efficacy of pulmonary resection for osteosarcoma lung metastases.
    • To identify predictors of long-term survival in patients undergoing this procedure.

    Main Methods:

    • Retrospective analysis of thirty patients with pulmonary osteosarcoma metastases.
    • Review of surgical procedures, including thoracotomies and lesion resections.
    • Assessment of survival rates and correlation with clinical factors.

    Related Experiment Videos

    Main Results:

    • Eleven of thirty patients were alive and disease-free at last follow-up.
    • Five-year survival rate was 28%, with some patients surviving over nine years.
    • Short tumor-free interval and multicentricity were adverse prognostic factors.
    • Long-term survival associated with >2-year tumor-free interval and limited metastases.

    Conclusions:

    • Pulmonary resection for osteosarcoma metastases can lead to long-term survival.
    • Patient selection and surgical approach are critical for favorable outcomes.
    • Resection offers survival advantage over no treatment for selected patients.