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Antibacterial and antifungal flavanones from Eysenhardtia texana
G A Wächter1, J J Hoffmann, T Furbacher
1Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson 85706, USA.
Phytochemistry
|January 27, 2000
Abstract:
An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana led to the isolation of two novel antibacterial and antifungal flavanones together with a known flavanone. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-[2-butenyl])-(2S)-flavanone, 4',5,7-trihydroxy-6-methyl-8-(3-methyl-[2-butenyl])-(2S)-flavanone and 4',5-dihydroxy-7-methoxy-6-(3-methyl-[2-butenyl])-(2S)-flavanone on the basis of their UV, 1D and 2D-NMR spectra.