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Related Experiment Videos

New terpenoids from Haplopappus multifolius.

G T Maatooq1, A A Gohar, J J Hoffmann

  • 1Department of Pharmacognosy, Faculty of Pharmacy, University of Mansoura, Egypt. galaltm@mans.edu.eg

Die Pharmazie
|May 10, 2002
PubMed
Summary
This summary is machine-generated.

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Researchers identified novel monoterpenes, a diterpene, and known dihydroflavones from Haplopappus multifolius aerial parts. Spectroscopic analysis confirmed the structures of these natural compounds.

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Organic Chemistry

Background:

  • Haplopappus multifolius is a plant species with potential medicinal properties.
  • The chemical constituents of plants are a rich source of novel bioactive compounds.

Purpose of the Study:

  • To isolate and characterize new and known chemical compounds from the aerial parts of Haplopappus multifolius.
  • To elucidate the structures of these isolated compounds using spectroscopic methods.

Main Methods:

  • Chemical investigation of plant extracts.
  • Isolation of compounds using chromatographic techniques.
  • Structure elucidation using spectroscopic measurements (e.g., NMR, MS).

Main Results:

Related Experiment Videos

  • Isolation of a new monoterpene, haplopappol (2,9-epoxy-p-menth-6-en-8-ol).
  • Isolation of a new monoterpenoid ester, haplofolin (9-cis-p-coumaroyloxy-alpha-terpineol).
  • Isolation of a new diterpene, 18-hydroxylabda-7,13Z-dien-15-oic acid, and its known E-isomer.
  • Identification of known dihydroflavones and dihydroflavonols.

Conclusions:

  • The chemical investigation led to the discovery of several new natural products.
  • The study expands the knowledge of the chemical diversity within the Haplopappus genus.
  • Spectroscopic data were crucial for the definitive structural assignments of all isolated compounds.