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Updated: Aug 14, 2026

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
Chemistry of sponges. 19. Novel bioactive metabolites from Hamigera tarangaensis
K D Wellington1, R C Cambie, P S Rutledge
1Department of Chemistry, and School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.
Abstract:
Seven new compounds (1-6 and 10) with a unique carbon skeleton have been isolated from the sponge Hamigera tarangaensis, and the structure of a previously reported metabolite has been revised from 12 to 8. The structures have been assigned from extensive NMR examination. Compounds 3-6 showed moderate in-vitro cytotoxicity against P-388, while 3 showed 100% in-vitro virus inhibition against both the Herpes and Polio viruses, with only slight cytotoxicity.

