Related Experiment Video
Updated: May 2, 2026

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits
Published on: June 2, 2019
Gangrene following intra-arterial injection of procaine penicillin
Abstract:
Irreversible ischaemic gangrene of the upper limb developed in a one-year-old child after an unintentional intra-arterial injection of procaine penicillin. The hand needed amputation. Arterial embolization phenomenon along with intense vasospasm appears to have been responsible for this rare complication. Unintentional intra-arterial injection of penicillin intended for intra-muscular use may lead to disastrous consequences. Regional tissue necrosis has been described previously but ischaemia leading to gangrene of an extremity has not been reported. The following is a case report of a child who developed such a gangrene in his hand which had to be amputated.
More Related Videos
Related Concept Videos
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization IV: Nursing Management
Peripheral Artery Disease V: Postoperative Nursing Management
Aneurysm III: Interprofessional Care
Imaging Studies VII: Vascular Imaging

