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Updated: Jan 3, 2026

Single-Cell Calcium Imaging for Studying the Activation of Calcium Ion Channels
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Single-Cell Calcium Imaging for Studying the Activation of Calcium Ion Channels

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Complex voltage-dependent behavior of single unliganded calcium-sensitive potassium channels

G Talukder1, R W Aldrich

  • 1Department of Molecular and Cellular Physiology, Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA.

Biophysical Journal
|February 2, 2000
PubMed
Summary

Investigating unliganded openings in the mSlo channel reveals complex gating behaviors. This study provides new insights into the mechanisms of allosteric ligand-gated ion channels, even without ligand presence.

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