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Updated: Sep 11, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
[Pulmonary complications of leukemia in children. A study of 72 cases (author's transl)]
Abstract:
A study was made of 72 cases of leukemia in children (the majority of which were acute lymphoblastic in type or with undiferenciated cells), in order to examine the type and frequency of pulmonary complications in leukemia, once complications of infectious etiology had been rejected. Pulmonary complications were found in 23 cases. Most often recurring image was the disseminated reticulonodular type. Nodular images and diverse pulmonary infiltrates were also discovered, these were often peribronchial and bilateral in almost every case. No significant relationship was found regarding the age of children, type of leukemia or length of time illness took to develop. Finally, present increase in the frequency of pulmonary complications in leukemia is commented and possible etiologic part antiblastic therapy might play on certain occasions is speculated.
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