Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neurophysiological imaging techniques in dementia.

G Comi1, L Leocani

  • 1Department of Neurophysiology, Scientific Institute Ospedale San Raffaele, University of Milan, Italy.

Italian Journal of Neurological Sciences
|February 9, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mitoxantrone prior to interferon beta-1b in aggressive relapsing multiple sclerosis: a 3-year randomised trial.

Journal of neurology, neurosurgery, and psychiatry·2011
Same author

Voxelwise assessment of the regional distribution of damage in the brains of patients with multiple sclerosis and fatigue.

AJNR. American journal of neuroradiology·2011
Same author

Thalamic damage predicts the evolution of primary-progressive multiple sclerosis at 5 years.

AJNR. American journal of neuroradiology·2011
Same author

Cortical lesions in children with multiple sclerosis.

Neurology·2011
Same author

Sensorimotor functional connectivity changes in amyotrophic lateral sclerosis.

Cerebral cortex (New York, N.Y. : 1991)·2011
Same author

A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex(®) ), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis.

European journal of neurology·2011
Same journal

Attualità in neurochirurgia : Edited by P. Paoletti, R. Kneich, R. Urcioli, C. Spairani Atti del XXXV Congresso Nazionale della Società Italiana di Neurochirurgia, September 1986. Mondadori Editore, 829 pages.

Italian journal of neurological sciences·2016
Same journal

24th Annual Meeting of the Italian Neuropathological Association : May 26-27-28, 1988 Napoli, Castel dell'Ovo.

Italian journal of neurological sciences·2016
Same journal

[Not Available].

Italian journal of neurological sciences·2016
Same journal

[Not Available].

Italian journal of neurological sciences·2016
Same journal

Pathogenesis and surgical treatment of neurovascular primary headaches.

Italian journal of neurological sciences·2016
Same journal

The complementary contribution of the rhinologist and the neurologist at the clinical study and treatment of the cluster headache.

Italian journal of neurological sciences·2016
See all related articles

Electroencephalography (EEG) offers high temporal resolution for studying brain function. Advanced EEG analysis, including spectral and coherence measures, aids in diagnosing dementia types and assessing cognitive function during tasks.

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Medical Imaging

Background:

  • Neurophysiological methods like electroencephalography (EEG) provide excellent temporal resolution for brain function analysis.
  • Advanced EEG techniques with numerous channels offer improved spatial resolution, aiding in brain function localization.
  • Integration with other imaging modalities enhances the ability to pinpoint brain functions.

Purpose of the Study:

  • To explore the utility of EEG and event-related potentials in investigating cognitive function in both healthy and pathological states.
  • To evaluate spectral and coherence analysis of resting EEG for assessing dementia and cognitive impairment.
  • To investigate task-related EEG activity for a deeper understanding of brain activation during cognitive and motor tasks.

Main Methods:

Related Experiment Videos

  • Utilizing electroencephalography (EEG) with high channel counts for enhanced spatial and temporal resolution.
  • Applying spectral analysis to resting EEG to assess cortical and subcortical network integrity.
  • Employing coherence analysis of resting EEG to measure functional cortico-cortical connections.
  • Studying event-related potentials and event-related desynchronization/synchronization during specific tasks.

Main Results:

  • Resting EEG spectral analysis shows decreased high-frequency power and increased slow-wave activity in dementia stages.
  • Centroid modifications in spectral analysis improve sensitivity for detecting abnormalities.
  • Coherence analysis reveals distinct patterns for Alzheimer's disease, cerebrovascular dementia, and multiple sclerosis-related dementia.
  • Task-related EEG measures (event-related potentials, desynchronization/synchronization) assess brain activation during cognitive and motor tasks.

Conclusions:

  • EEG, particularly advanced spectral and coherence analyses, is a valuable tool for assessing cognitive function and differentiating dementia types.
  • Task-based EEG analysis provides further insights into brain activity related to specific cognitive and motor processes.
  • EEG neurophysiological methods offer a powerful, non-invasive approach to understanding brain function in health and disease.