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[Relationship between perinatal pathology and refractogenesis, incidence and type of ocular diseases in children]
Insights
Children with perinatal disease history show significantly higher rates of ocular diseases, including severe visual impairments and myopia. Early referral for these children is crucial for timely intervention and management of potential vision problems.
Area of Science:
- Ophthalmology
- Pediatrics
- Neonatology
Background:
- Perinatal diseases can impact long-term child health.
- Ocular health is critical for child development.
Purpose of the Study:
- To investigate the incidence and types of ocular diseases in children with a history of perinatal diseases.
- To compare ocular health outcomes between children with and without perinatal disease history.
- To establish risk stratification for ocular disease in this population.
Main Methods:
- Comparative analysis of ocular health in 3-year-old children.
- Inclusion of children with and without a history of perinatal diseases.
- Statistical analysis to determine significant differences (p < 0.001).
Main Results:
- Children with perinatal disease history had a 78.9% incidence of ocular diseases versus 21.6% in controls.
- Common conditions included oculomotor disorders (20.8%), eyelid deformities (19.7%), and myopia (19.8%).
- Severe visual impairments such as optic nerve atrophy and cortical blindness were also noted.
Conclusions:
- Children with a history of perinatal diseases are at high risk for developing ocular diseases.
- Comprehensive ophthalmological screening is recommended for all children with perinatal disease history.
- Early detection and management are vital for preventing severe visual impairment.
Abstract:
Three-year-old children with a history of perinatal diseases differed from healthy age-matched children by a higher incidence of ocular diseases (78.9% vs. 21.6% in the control, p < 0.001). These children often presented with severe visual disorders: partial atrophy and hypoplasia of ocular nerves (7.2%), congenital abnormalities in the eyeball membranes (5.2%), retinopathy neonatorum (5.2%), cortical blindness (3.1%), oculomotor disorders (20.8%), and congenital deformations of the eyelids (19.7%). Disorders of refractogenesis in these children presented as a higher incidence of myopia (19.8% vs. 3.8% in the control, p < 0.001) and a shift of the percentage of refraction abnormalities towards myopia. Therefore, all children with a history of perinatal disease should be referred to a group at a high risk of ocular disease.
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