Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Sertoli-Leydig tumor. Clinical case].

A Huneeus1, F Alba, W Fernández

  • 1Instituto de Investigaciones Materno Infantil, Universidad de Chile.

Revista Medica De Chile
|February 11, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hallucinations and parkinsonian motor fluctuations.

Behavioural neurology·2014
Same author

Expanded allogeneic adipose-derived stem cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: results from a multicenter phase I/IIa clinical trial.

International journal of colorectal disease·2012
Same author

Metabolism of dehydroepiandrosterone sulfate and estrone-sulfate by human platelets.

Physiological research·2012
Same author

Angiotensinase and vasopressinase activities in hypothalamus, plasma, and kidney after inhibition of angiotensin-converting enzyme: basis for a new working hypothesis.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2011
Same author

Blood pressure increased dramatically in hypertensive rats after left hemisphere lesions with 6-hydroxydopamine.

Neuroscience letters·2011
Same author

Distribution of HLA alleles and haplotypes in the Maldivian population.

Tissue antigens·2011

A rare ovarian tumor, Sertoli-Leydig, was diagnosed in a 16-year-old girl with secondary amenorrhea and hirsutism. Surgical removal of the left ovarian tumor was successful, confirming the diagnosis.

Area of Science:

  • Gynecologic Oncology
  • Reproductive Endocrinology
  • Pathology

Background:

  • Sertoli-Leydig cell tumors are rare ovarian neoplasms, typically presenting in young women.
  • These tumors can cause significant hormonal disturbances, leading to symptoms like amenorrhea and hirsutism.
  • Obesity, indicated by a high body mass index (BMI), can sometimes be associated with gynecological conditions.

Observation:

  • A 16-year-old female presented with secondary amenorrhea, voice coarsening, hirsutism, and a BMI of 35 kg/m2.
  • Pelvic ultrasound and CT scans revealed a dense retro-uterine mass.
  • Surgical exploration identified a left ovarian tumor.

Findings:

  • Pathological examination confirmed the excised ovarian tumor as a Sertoli-Leydig cell tumor.

Related Experiment Videos

  • This diagnosis explains the patient's hormonal symptoms and virilization.
  • The tumor was successfully removed surgically.

    • Implications:

    • Early diagnosis and surgical management are crucial for favorable outcomes in Sertoli-Leydig tumors.
    • This case highlights the importance of investigating hormonal abnormalities in adolescent girls.
    • Further research into the hormonal milieu and potential genetic factors associated with these tumors is warranted.